In the pioneering development, the researchers designed a highly sensitive and selective sensor to use carbon fiber microchaser to detect copper (CU (II)) ions. This innovation method is described in detail in the latest publications in the Magazine of RSC, which represents a major leap in the field of electrochemical sensing.
The research team led by Dr. Yangguang OU, including Dr. David Punihaole, the University of Vermont University, has developed a platform based on ETHYNYL connecting anode deposition, especially 1,4-two ethylinier (Deb), and DEB. ),, Deb) ,,,,,,, Deb) ,,,, Deb), DEB), DEB), DEB), ETHYNYLBENZENE (DEB), DEB), ETHYNYLBENZENE, EXYNYLBENZENE, EVE. Carbon fiber microex. Dr. OU emphasized the novelty and potential impact of their work: “This research is the first to prove that the acetylene connector has the anode deposition of the acetylene connector to the carbon fiber microcircular electrode. Flat the road “
Copper ions play a vital role in various biological processes, including enzyme function and nerve signals. However, their disorders are related to severe diseases, such as Alzheimer’s disease. The traditional method of measuring copper involves complex and time -consuming procedures. The new sensor provides a simpler and more effective alternative solution, which can maintain high performance even when there are other interference metal ions.
The team’s method involves the direct DEB. The single -step anode sedimentation has significantly improved the sensitivity and selectivity (II) of the microstrone to CU. Researchers have shown that compared with the unmodified electrodes, DEB’s multiple scanning sedimentation causes the sensitivity of microelectrodes to threefold. The modified sensor retains the enhanced performance after a few days at room temperature, marking the significant improvement of existing technology.
In the experimental environment, researchers have found that more DEB modified electrodes show the increase in current density of the CU (II) reduction peak, indicating higher sensitivity. In addition, even when testing with other two -price metal ions (such as magnesium (Mg (II)), zinc (zn (ii)) and calcium (CA (ii)) are tested, these sensors also maintain the sensitivity of elevation. This kind of opposition to interference emphasizes the practicality of new sensors in the real world.
Dr. OU explained the meaning of their discovery: “Our work shows that these DEB modified microelectrodials can be used as a multi -functional platform for detecting copper ions in various biology and environment. This may lead to a better diagnosis Tools and more precise monitoring of copper -related crafts. “
The team’s comprehensive method includes the use of scanning electron microscope (SEM) to evaluate the surface shape of the modified electrode. These images show that the multi -scanning DEB deposition produces an uneven surface of the island -like structure. It may increase the sensitivity to increase the sensitivity by creating CU (II) deposition in the CU (0).
In short, the development of these DEB modified carbon fiber microelectrodes represent the major progress of electrochemical sensing technology. The sensitivity, selectivity and stability of these sensors make them a promising tools that have various applications from medical diagnosis to environmental monitoring. The work of Dr. OU’s team has opened up new ways to explore and understand the dynamics of copper in the biological system, which may lead to breakthroughs in disease -related disease -related diseases.
Journal reference
U. Nudurupati, Narla, T., Punihaole, D. And u, y. (2023). A convenient method for creating sensitive and selective CU (II) sensors on carbon fiber microdermia. RSC Advances, 13, 33688-33695. Doi: https: //doi.org/10.1039/d3ra05119f
About the author
Yangguang uThe doctoral degree is an assistant professor who joined the UVM chemistry in the fall of 2020. She is also a graduate course, honeycomb, honeycomb, molecular and biomedical science programs, and the brain health of cardiovascular and cardiovascular and cardiovascular disease centers in Vermont. Her research lies in the interface between biological analysis chemistry and neuroscience. Her laboratory is specifically scanning the cycle of the cycle on the carbon fiber microcompiral. Her long -term goal is to develop a multi -functional electrochemical sensing platform in order to detect any chemical biomarkers that are interested in. This will allow expansion of personalized diagnostic equipment to evaluate personal mental health, nutrition, stress, or other individual’s neurochemical state.
David Punihaole (David Punihaole)Doctorate is a chemical assistant at the University of Permon and serves as a graduate student of the Materials Science Program. He is also the person in charge of the research project of Cardiovascular and Brain Health Center (VCCBH) in Vermont. His research lies in the intersection of analysis and physics and biophysics, material science and neuroscience. His research team focuses on the development of chemical imaging tools that can directly visualize molecular -level structural dynamics and non -common price interactions of molecules in living cells. David’s group is interested in using this new imaging technology to study the protein folding regulatory mechanism to understand the structural foundation of amyloid -like protein fiber toxicity in neurodegenerative diseases (such as Alzheimer’s disease) The structural relationship of the nanoparticle delivery vehicle is used to transport drugs and treat nucleic acids in gene/cancer therapy.
Uma Current is 3road Annual graduate student studied for a PhD in chemistry degree under the supervision of Dr. Yangguang OU of the University of Vermont. She has a master’s degree in biophysics from UMASS AMHERST in the United States, studying structural proteins with light scattering, and she has the University of Hydraaba’s chemistry BS-MS. She has obtained the prestigious summer research scholarships enjoyed by the Indian Academy of Sciences twice, and works in fields covering protein science, materials science, spectrum and electrochemical fields. She contributed to the development of development on the Revbio LLC of Lael, Massachusetts, Massachusetts. Her research laid the foundation for the new product line. This product line involves non-opioid pain After the nursing, for the wisdom to extract. Outside the laboratory, she likes reading non -novel books, listening to classical music, hiking and fiber art.
Terdha narla It is the latest graduate of the Master of Pharmacology at the University of Volm. She has a bachelor’s degree in pharmacy in India, where she is engaged in the formula and evaluation of tablets. Due to her interest in brain chemistry and related diseases, she joined Dr. Yangguang OU’s group, where she developed electrochemical tools for two years. Essence During the OU laboratory, she co -authored two peer review publications published at the regional and international conferences, and developed her writing skills. In addition to these research efforts, Terdha also showed a commitment to education and guidance as a graduate assistant, and guided undergraduates in biology and neuroscience. In addition, she showed leadership through the secretary and vice president of the club of the two graduate leaders. Terdha was forced to learn new technologies and better understand the occurrence of brain physiology and neurosis. Her goal is to contribute to the development of treatment and diagnostic tools.
