Melatonin is a kind of hormone that is mainly known for regulating sleep. It has become a promising drug in the struggle with virus, bacteria and parasitic infections. This discovery brings hope for innovative treatment in the medical community. The motivation of this study is to explore the multi -faceted effects of melatonin in immune response regulation, antioxidant activity, and potential treatment for potential therapy applications for a series of diseases.
Dr. Georges Maestroni at the Insubria University of Medical Pharmaceutical Research led a comprehensive study that studied the impact of melatonin on various infections. These discoveries are published in the biomolecules of peer review journals. Dr. Maestroni discusses how melatonin synthesized in pinecasters and surrounding organs how to stimulate immune response, reduce inflammation and may act as the treatment agent for infection.
The study emphasizes the dual effect of melatonin: its day and night rhythm, enhance the immune response and its non -fibrosis, and can provide antioxidants and anti -inflammatory effects. This dual function may provide a balanced and effective immune response for microbial pathogens. Dr. Maestroni explained: “Melale melatonin can integrate its day and night rhythm and non -Circadian functions.
The significant results were noticed in the virus infection models of various models. For example, melatonin infection with the protection of meningitis virus and respiratory synthesis viruses by reducing oxidation stress and inflammatory reactions. During the COVID-19 period, several studies have studied the treatment potential of melatonin, and the results were mixed. Although some studies have reported the benefits of complication and mortality of severe patients, other studies have found that there is no significant impact on the survival rate. Dr. Maestroni emphasized: “The various doses and treatment timetables used in these studies have misunderstood the therapeutic characteristics of melatonin.”
In bacterial infection, melatonin shows hope in improving the ending of the sepsis model. For example, it enhances the survival and improvement of the bacterial removal rate of newborn in mice infected with Golden Pyranium. In addition, in the study of pneumonia involving methacotin two beetles, the potential of melatonin against antibiotics against antibiotics is emphasized. It must be emphasized that antibiotic resistance is a serious health issue in the world. The study emphasizes the dosage of melatonin and a better understanding of the planning plan, and exerts its therapeutic effect to the greatest extent.
Regarding parasitic infection, melatonin has a protective effect on malaria and cones. In the rodent model, the melatonin has improved the immune response and reduced the parasitic load. It is worth noting that melatonin can prevent brain damage and cognitive impairment in the cerebral malaria model. These findings show that melatonin may be a precious auxiliary therapy for managing parasitic infection.
The conclusion obtained by the study is that although melatonin shows important potential in confrontation, it requires more research to fully understand its mechanism and optimize its treatment. Dr. Maestroni said: “The integration of melatonin’s immunity and anti -inflammatory effect can provide strong tools for struggle with infection.”
All in all, this research has opened up new ways to explore the role of melatonin. By using its immune regulation and antioxidant specialty, melatonin may become an important part of the treatment of various infectious diseases. Dr. Maestroni believes that future research is essential for improving the therapy based on melatonin -based therapies and establishing a standard plan for its clinical application.
Journal reference
Maestroni, Georges JM “melatonin is used in virus, bacterial and parasitic infections.” Biomolecules, 2024, 14, 356. Doi: https: //doi.org/10.3390/biom14030356
About the author
George MasterBorn in Lausanne, Switzerland in 1947, graduated from Milan State University, Italy in 1973. In 1975, he joined the group of Professor E. Sorkin. Research activities on the relationship between the brain and the immune system. After conducting a research stage at the Weizman Institute of Rezmann in Request, Israel in 1977, he worked at the Institute of Anatomy at the University of Zurich. Until 1981 he moved to the Swiss Institute of Pathology and there was he. Provide funds, support it there, have guidance, and have guidance and guidance to the experimental pathology center in 2008. Dr. Maestroni now covers the position of a scientific consultant of the University of Pharmaceutical Center of Insubria University of Italy. In his career, Dr. Marstiani took the lead in studying the research on the immune effect of melatonin and the sympathetic nervous system regulation of the sympathetic nervous system.
