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How do you protect cells from aging?

Scientists have discovered a promising new approach that can reduce aging at cellular levels using a special whey protein (diet MAF). A team of researchers led by Dr. Toshio Inui studied the effects of this modified whey protein on chromosomes, known as protective caps for telomeres, in young and older mice. Their findings, published in the journal Scientific Reports*, suggest that the protein may help maintain cell health and slow down the natural aging process.

Telomeres are like plastic tips on shoelaces, and they protect chromosomes from damage. However, as age increases, these telomeres gradually shorten, leading to increased risk of cellular aging and age-related diseases. Chromosomes that carry genetic information in cells rely on telomeres to maintain stability and function. The researchers compared the effects of modified whey protein with conventional whey protein to see that it has a greater impact on telomere length. They found that mice consuming modified whey protein for several weeks showed a significant increase in telomere length. “We found that modified whey proteins, but not conventional whey proteins, significantly prolong telomeres and enhance the activity of key genes responsible for maintaining them,” explains Dr. Inui. The protein also increases the production of molecules required for telomeres repair and maintenance, which helps prevent DNA damage and slow down cell aging.

In young mice, telomeres increased by several weeks after telomere length, while conventional whey protein had only a small effect. However, the most compelling results were observed in older mice, which naturally had shorter telomeres. After consuming modified whey protein, the mice recovered the telomere length comparable to that of the younger mice. The researchers also pointed out that the production of molecules essential for telomeres in mice has significantly improved, bringing them to similar levels to those in young mice.

The findings of Dr. INUI’s team suggest that modified whey protein may help protect genetic material and reduce the aging process at cellular levels. Genetic substances, including DNA, contain instructions to control cellular function and overall health. “The significant telomeres observed in young and older mice highlight the potential of this whey protein as a dietary supplement to maintain long-term cellular health,” said Dr. Inui. Because shorter telomeres are associated with a variety of aging-related diseases, including heart disease and neurodegenerative diseases, which affect the brain and nervous system, this discovery may pave new strategies for new strategies to promote healthier aging.

In addition to aging, shortened telomeres are also associated with mental health problems and chronic stress. Studies have shown that prolonged stress can accelerate telomere shortening, which can lead to mood disorders and other psychological conditions. Since it has the potential to retain telomere length, this modified whey protein may also be good for mental health. Mood disorders, such as depression and anxiety, are associated with imbalances in brain chemistry and prolonged stress, which may affect telomere health. Although these results are encouraging, further research is needed to understand exactly how proteins work and whether similar effects can be seen in humans.

The discovery of this ability of whey protein to expand telomeres marks an important step in nutritional science. Nutritional Science focuses on how diet and nutrients affect overall health and aging. As researchers continue to explore their applications, their potential role in promoting lifespan and protecting age-related decline remains a fascinating area for future research.

https://www.youtube.com/watch?v=I8G2CV_HF0U

Journal Reference

Inui T., Kawamura N., Yamamura M., Kubo K., Yamakage H., Satoh-Asahara N., Ogawa Y., & Katsuura G. “Organic intake of oral demactosylated whey protein increases peripheral blood telomeres in young mice.” Scientific Report, 2024. Doi:

About the Author

Dr. Toshio Inui He is the CEO of Saisei Mirai Clinic Group and an outstanding doctor with a PhD. He graduated from Kyoto Medical University in 1978. After graduation, he gained doctoral experience in the Department of Internal Medicine of General Hospital. At the age of 33, he founded the INUI clinic, which specializes in internal diseases. A critical moment in his career came after his father lost cancer, which led Dr. Inui to reevaluate the limitations of traditional cancer therapies, including surgery, chemotherapy and radiation. This personal experience prompted him to focus on immunotherapy as another way to treat cancer. As a result, he renamed his clinic to INUI Cancer Immunotherapy Clinic and is committed to advancing immunotherapy research and cancer treatment.
Today, his clinic has collaborated with universities and medical institutions in Japan and internationally to pioneer research and development in immunotherapy such as GCMAF, autologous cancer vaccine, Hyper T/NK cell therapy, SonodyNalnamic therapy (SDT), and P53 and PTEN gene therapy.
Key career highlights:
⚫1978: Graduated from Kyoto Medical University
⚫1987: Founded INUI Cancer Immunotherapy Clinic in Osaka
⚫2009: Established Saisei Mirai Medical Company
⚫2010: In Osaka, Kobe opened Saisei Mirai Clinic and Tokyo
⚫2013: Appointed as Visiting Professor at Kyoto University Medical University, Ritsumeikan University (2018) and Kagoshima University (2020)
⚫2016: Tokushima University received a Ph.D. in Engineering.
⚫2023: Opened Saisei Serbia Clinic; Saisei Lithuania Company