Chronic kidney disease and hypertension are serious health problems, and the impact on African -American is far greater than other groups. If it is not resolved, these conditions may lead to kidney failure and heart problems. To solve this problem, Dr. Meera Patel at the Southwest Medical Center of the University of Texas and Dr. Heather Kitzman explored how to help improve the health of African -American adults who challenged these challenges. Their discovery was published in the magazine of Metabolism, clarifying early signs of how simple diet changes have achieved something and determine the deterioration of health.
Dr. Heather Kitzman’s team has conducted intervention measures for the six weeks at Baylor Sott and White Health and Health Centers (Baylor Sott) and White Health and Health Centers. Suggesting two glasses of fruits and vegetables. The diet aims to reduce the harmful effect of some foods that produce acids in the body, thereby worsening the health of the kidneys and supporting better kidney and heart function. The study involves African Americans suffering from chronic kidney diseases (stages 1-3) and high blood pressure from poor communities in southern Dallas. These participants are divided into two groups: one group follows the intervention diet, and the other continues to eat. The research design enables Dr. Patel, the person in charge of the project, to compare two groups, and understand how diet will affect health over time.
This study shows that the health of people with diet and diet is small but hopeful. The changes in kidney health markers, such as the ratio of albumin to creatinine, can measure how much protein exudation in urine and indicates that renal function, weight, cholesterol level and blood pressure are not significant. A little improvement. Dr. Patt explained: “Although the result is initial, they show that the increased fruits and vegetable intake may help the long -term improvement of kidney and heart health.”
The key part of the study is a detailed analysis of the tiny substances (called metabolites) in the body. The substance is generated in the process of human metabolism and reflects the function of the body. By checking these substances, researchers have found that certain molecules in the human body are related to the risk of deterioration of renal function and heart problems. For example, a molecule called propyrine is processed with the human body to treat fat and may indicate stress in energy production. Another molecule called Kynurenine is related to inflammation. This is a natural response to the human body to damage or infection. This reaction may be harmful when extending. It also identified a compound called choline, which affects the liver and muscle health. Participants who follow the conventional diet have shown significant increases among these harmful elements, and the level of people who intervene in the diet are stable or slightly lower.
Researchers pointed out that the changes in these tiny substances may occur before obvious major health issues, which shows that the potential of this analysis is detected early. Dr. Patel shared: “Our discovery emphasizes the study of these small molecules with earlier discovery risk factors and creating more personalized strategies to help people improve health.”
The study also emphasizes the importance of factors such as income and obtaining nutritional foods, which plays an important role in managing long -term health issues. The participants of the plan obtained free fruits and vegetables, making diet easy to use, and showing how this method works in other communities and obtain fresh food.
Despite positive discovery, the study still faces some challenges. It lasted only six weeks, and researchers relied on participants to report their degree of diet. Future research will take a long time to fully understand the benefits of such diet and how they work with other treatment methods. Dr. Patt said to hope: “This research laid the foundation for greater experiments. These tests may change our views on preventing kidney and heart problems.”
This study shows that the potential of simple, affordable diet and advanced analysis of small substances in the body (a method called metabolic group analysis) to solve long -term health differences. This type of analysis provides metabolic health snapshots by analyzing these small molecules and their interaction methods in the body. This method provides a roadmap for creating targeted solutions, which can help people live a healthier life while reducing the risk of serious diseases such as kidney disease and heart disease.
Journal reference
Patel, MJ, EMERENINI, C., WANG, X., Bottiglieri, T., Kitzman, H. “Heart -protective diet intervention is a metabolic group and physiological role in adults with chronic kidney diseases with African -American.” Metabolism, 2024. Doi: https: //doi.org/10.3390/metabo14060300
About the author
Dr. Pattel It is a translator with more than 11 years of experience. In the past few years of academics and doctors, she carried out biomedical, molecules and hereditary research in the scientific laboratory and community -based environment. Patel’s academic career during the master’s degree and doctoral education includes protein groups and molecular studies of primary biology and eukaryotic systems to better understand protein function and pathogenesis. In order to conduct post -doctoral training, she was fortunate to work in Texas, Baylor Scott and Baylor Scott and Baylor Scott and White Health. In order to seek community -based clinical research experience. She continues to apply her own biomedical scientific background at the community level to better understand the health methods of population and improve chronic diseases in high -risk people. The main focus of Patel is to apply her transformation research background to community -based participation research and pragmatic trial research to solve the health differences between the vulnerable groups of society and improve the health status in a larger scale. At present, as a lecturer at the Peter O’Donnell Jr. School of Public Health, the UT Southwest Medical Center, she is a common evaluation of some pragmatic national clinical trial research.
Dr. Kizman Currently is an associate professor at the Peter J. O’Donnell Jr. School of Public Health at the Peter J. O’Donnell Jr. School of Public Health, and is also the director of the Office of Health and Research on the Office of the Office of the School of Public Health. She has carried out the transformation and clinical research of the community -funded community, which is related to chronic diseases in lower -income people. In the past two decades, Dr. Kizman’s research has been concentrated in random tests and queue studies in clinics related to chronic diseases and precision medicine, mainly low income and minority population. She has always been PI or CO-I with 40 scientific research and has more than 140 research products. As a PI management team, she has rich experience and can successfully recruit ethnic minorities participants to participate in large -scale multi -site national trials. Kitzman (Kitzman) is committed to improving the health results of minority and low -income people. It mainly focuses on development tools to improve access and participate in research, and spread the results to extensive audiences.
