Intestinal diet superhero: scientists cracked bacteria that promoted healthy, AkkerMansia Muciniphila

Scientists have unlocked the complex feeding mechanism of beneficial intestinal bacteria, which may be the key to understanding and treating various inflammatory diseases and metabolic diseases.

In a study published in natural microbiology, the researchers explained how akkermania mucosa (AM) -Micoor -related to better health results -systematically decompose sugar molecules in the intestinal protective mucus layer.

The research team led by Dr. Lucy Crouch, University of Birmingham, conducted the first comprehensive analysis of 66 different enzymes used to digest mucus sugar. Their discovery reveals a complex molecular process that allows this beneficial bacteria to reproduce in the human digestive system.

Dr. Croup said: “This is the first time we have seen how the microorganisms break down the food source O in the intestine.” This is the first time to use a set of enzymes to completely decompose sticky protein. “

The significance of this discovery exceeds basic science. New feature enzymes can be used as valuable tools for detecting the changes in polysaccharides produced by humans-it can indicate the complex sugar structure of various health conditions. These sugar molecules also act as attachments to harmful diseases and their toxins (including dangerous Zhiga toxins).

Researchers use pig models to study the mucus decomposition process, which proves that AM’s enzymes can fully decompose adhesive protein-feats that have never been realized in the laboratory environment. This breakthrough provides the first detailed understanding of any microorganism of how to deal with O chain sugar, these sugar is a key component of the intestinal protection barrier.

The impact of this study on human health is great. AM has become a key indicator of intestinal health. The low level of bacteria is related to inflammatory diseases and diabetes. Microorganisms are particularly sensitive to dietary fiber intake, highlighting the connection between the health of the diet and the intestinal microbial group.

According to Dr. Couich, the relationship between AM and human health surpasses simple digestion. She explained: “AM protein and outer membrane extract have been proven to have a positive impact on the host, including the beneficial impact of metabolism.” “Some of these proteins interact with host receptors and may suppress immune response.”

These findings have opened up new possibilities for the treatment of intestinal health and metabolic diseases. By understanding how AM handles these complex sugar structures, researchers may formulate new strategies to change glycosaccharides and may reduce the severity of the disease.

This study represents an important step in understanding the complexity between intestinal bacteria and human health, and provides new tools for the diagnosis and treatment of digestive and metabolic diseases.