A new study by researchers in China and the United States shows that entering the dream of sleep may be an early warning signal of Alzheimer’s disease, which provides new insights for the connection between sleep mode and brain health.
This research was published in Alzheimer’s disease and dementia on January 27: “Alzheimer’s Magazine Magazine” found that it took more than three hours to enter the rapid eye movement (REM) sleep. People show that the protein level related to Alzheimer’s disease is significantly higher.
“The delay of Rem sleep destroys the ability of the brain to consolidate memory by interference by interference,” said Dr. Yue Leeng, associate professor and research of the Department of Psychiatry and Behavior Science of Psychiatry and Behavior Science. Essence “If it is not enough or delay, it may increase pressure hormone cortisol.”
The research tracked 128 adults with an average age 70 and monitored their sleeping ways in Beijing’s China Friendship Hospital. Research team led by Dr. Leng and DANTAO PENG found that the starch -like protein of participants who reached the REM sleep time increased by 16 %, while the TAU increased by 29 % -two protein and Alzheimer’s disease Closely related.
Perhaps the most striking thing is that delayed REM sleep is related to the decrease in brain -derived neurotic nutritional factor (BDNF), which usually shows that the level of Alzheimer’s disease is reduced. This huge difference shows that changes in sleep may be more than just a symptom-they may be an early indicator of the disease process.
Rem sleep is the stage of most dreams, usually about 90 minutes after falling asleep. During this critical period, the brain will handle emotional memory and transfer it to long -term storage. The study divided the participants into two groups: participants who arrived in REM sleep within less than 98 minutes and participants in more than 193 minutes (delay group).
The meaning of these findings is not just the risk factors. Dr. Peng emphasized the importance of solving the problem of sleep -related problems that may affect ReM sleep. He pointed out: “This includes treating sleep apnea and avoiding drinking and other diseases, because both will interfere with a healthy sleep cycle.”
The research team suggested that drugs that affect the mode of sleep may work in changing the progress of the disease. Studies in mice have shown that melatonin that can enhance REM sleep may help reduce the accumulation of harmful protein related to Alzheimer’s disease. Similarly, certain insomnia drugs that are used by blocking REMs to suppress chemicals have potential to reduce these harmful proteins.
For those who are concerned about Alzheimer’s risk, researchers recommend discussing drugs that may be related to their healthcare providers, especially antidepressant drugs and antidepressants and sedatives related to this sleep stage.
This study represents an important step in understanding the complexity between sleep mode and Alzheimer’s disease. Although more research is required to fully understand these connections, the results show that monitoring REM sleep mode may help identify the risks of people with Alzheimer’s disease before the emergence of other symptoms.
The study was supported by the Ministry of Science and Technology of China and the National Health Commission of China, reflecting the growing international cooperation in the State Cause of Alzheimer’s disease.
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