Scientists have discovered the “blood fingerprint” of children’s new coronal virus, paving the road for the first diagnosis and testing

Italian researchers have found a unique molecular characteristics in children’s blood that proves that this disease has a clear biomarker, which may change the way doctors’ diagnosis and treatment of long -crown viruses for young patients may change. This pioneering study published in the Pediatric Research Magazine shows that the long -crown virus among children is similar to the inflammation model in adults, which effectively ended the dispute over the existence of physical foundation in young people.

The research team used advanced protein analysis and artificial intelligence to check the blood samples of 112 children, and compared those children with long -term new crown pneumonia with other children with acute new crown pneumonia, inflammatory complications or no history of infection. Studies have found that children with long -crown virus show a unique inflammatory protein model in the blood, which is different from all other groups.

“This work is irrelevant to show that long -acting new crown pneumonia (also in pediatric age) is a disease -based immune -mediated disease that requires new funds to study the best treatment method,” the chief researcher of Catholic Catholic University Dr. Danilo Buonsnso said a pediatrician of Fondazione Policlinico Gemlli IRCCS.

Researchers have developed an artificial intelligence model that can identify new crown cases with 93% accuracy, which brings hope for the first objective diagnosis and testing of the disease. This model detects 86%according to the hemophil mode detection cases, and the sensitivity is 97%.

The most important thing is that the study found that eight specific inflammatory proteins have continued to rise among children with new crown pneumonia, including CXCL11, CXCL1, and CXCL8, which play a vital role in inflammation and blood vessel formation. This protein characteristics reflect the model observed in previous patients with adult Long Covid, indicating that the potential disease mechanism of each age layer is similar.

Dr. Nicola Cotugno, a children’s hospital, explained: “The immunology data generated in this study provides evidence to determine the treatment target in order to test the effectiveness and safety research of pediatrics Long Covid.”

Studies include strict control. Children who have long-term virus infected with new crown viruses are compared with 32 active infected children, 27 children’s inflammation syndrome (MIS-C) children and 19 health controls. All children in the Changxin Crown Virus have been infected for at least eight weeks after the initial infection, and its impact is enough to disrupt daily activities.

Researchers have found that the content of FGF21 in children with continuous fatigue is particularly high. FGF21 is a protein involving energy metabolism and muscle function. This discovery is consistent with the recent adult research. It linked the long -term new crown fatigue and mitochular functional disorders, and proposed a potential treatment pathway.

This study represents a major step in understanding the new crown pneumonia, and the disease has affected about 0.5% of children who have touched SARS-COV-2. Although this situation is not as common as adults, it especially affects children over 10 years old, no matter how serious their initial infection is.

These findings may lead to the development of conventional blood testing for children’s long -coronal virus, which may completely change the recognition and treatment of this disease. The discovery of specific biomarkers has also opened a new way for target therapy, bringing hope to the family who struggle with this challenging disease.

Looking forward to the future, the research team has begun to collect subsequent samples to track how these blood markers changes in the process of child rehabilitation, so as to deeply understand the duration and treatment effect of the disease. The author emphasizes that a larger -scale test is required to verify these discoveries and develop standardized diagnostic tests.